Two solid blasts from the super shotgun or five well placed shots from the shotgun will reliably kill a Revenant. When fighting larger groups of these towering skeletons, it is useful to use a plasma gun, the BFG9000 or a rocket launcher. On harder difficulties, they are often found in large groups, especially out in the open. If they do not, the melee attack of the Revenant delivers a fiendishly powerful blow that can easily crush the player with a few hits, so therefore melee attacks are strongly discouraged. The Revenant is rather fast on its feet, so players must be sure to keep their distance. The chainsaw is also powerful but quite risky due to exposition to a possible missile fired, unless the player can quickly catch the creature off-guard and slash it in time. Fortunately, the pain chance of a Revenant is rather high, so a chaingun will generally suffice against a single monster, preventing it from attacking.

The Revenant's missiles are very powerful and when homing, particularly hard to dodge when out in the open. Thankfully, they are fairly sensitive to pain, and when hurt, will bend backward at an exaggerated angle, giving off a cry of pain. When a Revenant is within 196 units of its target, it will resort to its punching attack, unless attacked and hurt, where it counter-attacks with a missile. During melee combat they can also strike a blow with one of their large fists, complete with an exaggerated punching sound effect. The homing missiles can be identified by their gray smoke trail. Revenants fire two sorts of missiles unguided and homing. Revenants are fast runners, but unlike Demons or Spectres, run directly at their target rather than zigzagging aimlessly, and are also quick to fire their missiles or punch any nearby targets, making them quite dangerous due to their speed. When killed, a few of the Revenant's bones will shatter, creating a very distinct crunching sound, and the monster will simply fall on its back, one of the cleanest monster deaths the player will come across. While active and within earshot, they give off a heavy huffing breathing sound. A Revenant emits a raging/pain-like high-pitched scream, like a roaring 'AAAAA!', when spotting the player.

Doom 2 revenant